Slowing of sodium channel opening kinetics in squid axon by extracellular zinc.
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چکیده
منابع مشابه
Slowing of sodium channel opening kinetics in squid axon by extracellular zinc
The interaction of Zn ion on Na channels was studied in squid giant axons. At a concentration of 30 mM Zn2+ slows opening kinetics of Na channels with almost no alteration of closing kinetics. The effects of Zn2+ can be expressed as a "shift" of the gating parameters along the voltage axis, i.e., the amount of additional depolarization required to overcome the Zn2+ effect. In these terms the me...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1982
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.79.6.935